Probiotic | Placebo | Unadjusted | Adjusted | |||||
---|---|---|---|---|---|---|---|---|
n | % | n | % | OR(95% CI) | OR(95% CI) | |||
Primary outcome | ||||||||
Allergic disease | 145/461 | 31.5 | 163/464 | 35.1 | 0.85(0.64-1.12) | .236 | 0.82(0.61-1.08) | .159 |
IgE-associated allergic diseases | 64/456 | 14. | 87/463 | 18.8 | 0.71(0.50-1.00) | .052 | 0.65(0.45-0.94) | .022 |
Secondary outcome | ||||||||
Eczema | 120/461 | 26.0 | 15/464 | 32.3 | 0.74(0.55-0.98) | .035 | 0.69(0.52-0.93) | .015 |
Atopic exzema | 57/459 | 12.4 | 82/463 | 17.7 | 0.66(0.46-0.95) | .025 | 0.61(0.42-0.90) | .012 |
Sensitization | 127/454 | 28.0 | 144/462 | 31.2 | 0.86(0.65-1.14) | .289 | 0.82(0.61-1.10) | .0184 |