Table 2. 출생 후 6개월 동안 프로바이오틱스와 갈락토올리고당을 섭취한 영아~2세 나이의 알러지질환 발생율 및 아토피성 습진 변화

Probiotic Placebo Unadjusted Adjusted*
n % n % OR(95% CI) p value OR(95% CI) p value
Primary outcome
 Allergic disease 145/461 31.5 163/464 35.1 0.85(0.64-1.12) .236 0.82(0.61-1.08) .159
 IgE-associated allergic diseases§ 64/456 14. 87/463 18.8 0.71(0.50-1.00) .052 0.65(0.45-0.94) .022
Secondary outcome
 Eczema 120/461 26.0 15/464 32.3 0.74(0.55-0.98) .035 0.69(0.52-0.93) .015
 Atopic exzema 57/459 12.4 82/463 17.7 0.66(0.46-0.95) .025 0.61(0.42-0.90) .012
 Sensitization 127/454 28.0 144/462 31.2 0.86(0.65-1.14) .289 0.82(0.61-1.10) .0184
Values in boldface are statistically significant.
Adjusted by means of multivariable losistic regression for sex, delivery by means of cesarean section, breast-feeding for at least 6 months, use of antibitics during the intervention, and regular (daily or ≥2 days a week) use of probitics after the interventions.
The p value was calculated by using logistic regression analysis.
Food allergy, eczema, asthma, or allergic rhinitis.
Food allergy, eczema, asthma, or allergic rhinitis in infants with positive skin prick test responses or antigen-specific IgE levels of greater than 0.7 kU/L.
Eczema in infants with positive skin prick test responses or serum antigen-specific Ig E levels of greater than 0.7 kU/L.
Positive skin prick test response or serum antigen IgE level of greater than 0.7 kU/L.